Figure 9.

Time-course of the double-labeling of TDO with bromodeoxyuridine (BrdU) in the dentate gyrus (DG) granule cells. A: The images are representatives of double-labeling of BrdU and TDO at 4 wk after injection of BrdU. Arrowhead indicates the same cell in each line. g, granule cell layer; h, hilus. B: Changes in co-labeling rates of BrdU with TDO in the DG over a period of 4 wk after injection of BrdU are shown. Values are given as the means ± SEM of the analysis based on the results of three mice. The asterisk and double asterisk indicate statistically significant differences: *, p < 0.05; **, p < 0.01 (one-way ANOVA and Scheffé's post hoc test).