Research

Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization

Min Wang¹, Lin Pei¹, Paul J Fletcher^1,^3,⁴, Shitij Kapur², Philip Seeman⁵ and Fang Liu^1,^4,⁶^*

¹ Department of Neuroscience, Centre for Addiction and Mental Health, Toronto, Ontario, M5T 1R8, Canada

² Institute of Psychiatry, University of London, London, SE5 8AF, UK

³ Department of Psychology, University of Toronto, Ontario M5S 3GS, Canada

⁴ Department of Psychiatry, University of Toronto, Ontario, M5T 1R8, Canada

⁵ Department of Pharmacology and Toxicology, University of Toronto, Ontario, M5S 1A8, Canada

⁶ Department of Neuroscience, Centre for Addiction and Mental Health, Clarke Division, 250 College Street, Toronto, Ontario M5T 1R8, Canada

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Molecular Brain 2010, 3:25 doi:10.1186/1756-6606-3-25

Published: 2 September 2010

Additional file 1:

Specificity of D2R antibody. Western blot analysis of dopamine receptor D2 dimer and monomer expression in both rat and human striatal extracts.

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