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Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

Masaaki Kanai1, Hiroshi Funakoshi1, Hisaaki Takahashi1,2, Tomoko Hayakawa1,3, Shinya Mizuno1, Kunio Matsumoto1,4 and Toshikazu Nakamura1,5*

1 Division of Molecular Regenerative Medicine, Department of Biochemistry and Molecular Biology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

2 Department of Molecular and Cellular Biology, School of Medicine, Ehime University, Ehime, Japan

3 Department of Vascular Regeneration, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

4 Division of Tumor Dynamics and Regulation, Kanazawa University Cancer Research Institute, Kanazawa, Japan

5 Kringle Pharma Joint Research Division for Regenerative Drug Discovery, Osaka University, Osaka 565-0871, Japan

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Molecular Brain 2009, 2:8 doi:10.1186/1756-6606-2-8

Published: 27 March 2009

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Additional file 1:

Supplementary methods, Supplementary Tables S1-S2, and Supplementary Figures S1-S3 are included in this file.

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