Table 1 |
|||
|
Motors and adaptors for transport of synaptic cargos |
|||
| Cargo |
Adaptor |
Motor |
Reference |
|
|
|||
| Receptor |
|||
| NMDA Receptor (NR2B) |
CASK/MALS/Mint |
KIF17 |
[89] |
| AMPA Receptor (GluR1/GluA1) |
SAP-97 |
Myosin VI |
[130] |
| Myosin V |
[46] |
||
| AMPA Receptor (GluR2/GluA2) |
GRIP1 |
KIF5 |
[88] |
| Glycine Receptor (GlyR) |
Gephyrin/DLC |
Dynein |
[131] |
| Reelin Receptor (APOER2) |
JIP |
KIF5 |
[80] |
| Trk Receptor (TrkB) |
Rab27B/Slp1/CRMP-2 |
KIF5 |
[127] |
| DLC |
Dynein |
[73] |
|
| GIPC1 |
Myosin VI |
[133] |
|
| Synaptic Vesicle Precursor (SVP) |
|||
| VAMP2/SYP |
Myosin V |
[134] |
|
| Rab3 |
DENN/MADD |
KIF1A/KIF1Bβ |
[104] |
| PIP2 |
KIF1A |
[66] |
|
| unknown |
Liprin-α |
KIF1A |
[91] |
| Piccolo-Bassoon Transport Vesicle (PTV) |
|||
| Bassoon |
DLC |
Dynein |
[135] |
| Syntaxin-1 |
Syntabulin |
KIF5 |
[136] |
| SNAP-23/25 |
KIF5 |
[137] |
|
| Mitochondria |
|||
| Miro |
Milton |
KIF5 |
[83] |
| unknown |
JIP |
KIF5 |
[138] |
| unknown |
Syntabulin |
KIF5 |
[139] |
| unknown |
unknown |
Dynein |
[82,140] |
| Endosomes |
|||
| Rab5 |
VPS34 |
KIF16B |
[97] |
| Rab5 |
HAP40 |
unkown |
[98] |
| Rab4 |
KIF3 |
[99] |
|
| Rab4 |
LIC |
Dynein |
[100] |
| Rab7 |
RILP |
Dynein |
[101,102] |
| Rab11 |
FIP2 |
Myosin V |
[45] |
| PSD protein |
|||
| PSD-93, PSD-95, S-SCAM, |
KIF1Bα |
[94] |
|
| SAP102, SAP97 |
|||
| GKAP |
DLC |
Dynein |
[93] |
| RNA Particle (RNP) |
|||
| unkown |
KIF5 |
[41] |
|
| FMRP |
KIF5/Dynein |
[42] |
|
| FMRP |
KIF3C |
[43] |
|
| TLS |
Myosin V |
[34] |
|
|
|
|||
|
Schlager and Hoogenraad Molecular Brain 2009 2:25 doi:10.1186/1756-6606-2-25 |
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