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Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders

Nobuyuki Yamasaki1,2,3,4* email, Motoko Maekawa3,5* email, Katsunori Kobayashi3,6* email, Yasushi Kajii7* email, Jun Maeda8* email, Miho Soma5* email, Keizo Takao1,3,4,9* email, Koichi Tanda1,3,4 email, Koji Ohira3,4,9 email, Keiko Toyama1,3,4,9 email, Kouji Kanzaki7 email, Kohji Fukunaga10 email, Yusuke Sudo11 email, Hiroshi Ichinose3,11 email, Masashi Ikeda3,12,13 email, Nakao Iwata3,12 email, Norio Ozaki3,13 email, Hidenori Suzuki6 email, Makoto Higuchi8 email, Tetsuya Suhara8 email, Shigeki Yuasa3,5 email and Tsuyoshi Miyakawa1,3,4,9,14 email

Genetic Engineering and Functional Genomics Group, Frontier Technology Center, Kyoto University Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Japan

Department of Psychiatry, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, Japan

Japan Science and Technology Agency, CREST, Saitama, Japan

Japan Science and Technology Agency, BIRD, Saitama, Japan

Department of Ultrastructural Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-higashi, Kodaira, Tokyo, Japan

Department of Pharmacology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan

Mitsubishi Tanabe Pharma Corporation, 1000 Kamoshida-cho, Aoba-ku, Yokohama, Japan

Department of Molecular Neuroimaging, Molecular Imaging Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Japan

Division of Systems Medicine, Institute for Comprehensive Medical Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Japan

10  Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai, Japan

11  Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Japan

12  Graduate School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Japan

13  Graduate School of Medicine, Nagoya University, 65 Tsuruma-cho, Showa-ku, Nagoya, Japan

14  Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan

author email corresponding author email* Contributed equally

Molecular Brain 2008, 1:6doi:10.1186/1756-6606-1-6

Published: 10 September 2008

Additional files

Additional file 1:

Supplementary figures. Supplementary Figures S1–S14 are included in this file.

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Additional file 2:

Supplementary tables. Supplementary Tables S1–S5 are included in this file.

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