Research
Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia
-
* Corresponding author: Ryota Hashimoto hashimor@psy.med.osaka-u.ac.jp
1 Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan
2 Genetic Engineering and Functional Genomics Unit, Frontier Technology Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
3 Japan Science and Technology Agency, CREST (Core Research for Evolutionary Science and Technology), Kawaguchi, Saitama, Japan
4 Japan Science and Technology Agency, BIRD (Institute for Bioinformatics Research and Development), Kawaguchi, Saitama, Japan
5 Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
6 Department of Psychiatry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
7 The Osaka-Hamamatsu Joint Research Center for Child Mental Development, Suita, Osaka, Japan
Molecular Brain 2008, 1:11 doi:10.1186/1756-6606-1-11
Published: 22 October 2008Additional files
Additional file 1:
Reduced locomotor activity in sdy mice in an open field test. (A) Total locomotor distance. (B) Count of vertical activity. (C) Time spent on the centre of the field. (D) Count of stereotypic behavior. Data were analyzed by two-way repeated measures ANOVA.
Format: PDF Size: 162KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 2:
Reduced locomotor activity in sdy mice in a light/dark transition test. (A) Distance traveled in the light and dark boxes. (B) Time course of the distance traveled in the dark box. (C) Time spent in the light box. (D) Number of transitions between the light and dark boxes. (E) Latency of first entry into light box. Data were analyzed by two-way ANOVA and two-way repeated measures ANOVA.
Format: PDF Size: 137KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 3:
Normal anxiety-like behavior in sdy mice in elevated plus maze test. (A) Total number of arm entries. (B) Percentage entries into open arms. (C) Distance traveled. (D) Percentage entries into open. Data were analyzed by two-way ANOVA and two-way repeated measures ANOVA.
Format: PDF Size: 101KB Download file
This file can be viewed with: Adobe Acrobat Reader